Magnesium is predominantly found intracellularly, where it is vital for proper cell functions. Magnesium is the second most prevalent intracellular cation (after potassium). Magnesium functions are numerous and essential, including enzyme activation (over 300 types), neuromuscular activity, membrane transport and interactions, energy metabolism (carbohydrates, fats, proteins), and roles in calcium and phosphorus metabolism.
Deficiency Symptoms
Deficiency symptoms are both acute (Trouseau and Chvostek signs, muscle spasms, tetany, cardia arrythmias, ataxia, vertigo, convulsions, organic brain syndrome) and chronic (thrombophlebitis, hemolytic anemia, bone loss, depressed immune function, poor wound healing, hyper irritability, burxism, hyperlipidemia, fatigue, hypertension). Those at risk for Magnesium deficiency include: malabsorption, malnourished, alcoholics, diabetics, diuretic therapy, children, elderly, pregnant and lactating women, post menopausal women with osteoperosis, athletes, digitalis therapy, long-term therapy with antibiotics, chemotherapeutic and immunosuppressive medications. In addition, the following diseases are associated with Magnesium deficiency: cardiovascular disease, cirrhosis, renal disease, parathyroid diseases, thyroid conditions.
Repletion Information
Dietary sources richest in Magnesium (per serving) are:
- Nutritional Supplements
- Seeds (especially pumpkin)
- Nuts
- Soybeans
- Whole Grains
- Potatoes
- Legumes
- Fresh Vegetables
Watch or download Dr. Grabowski's presentation on "Connecting the Nutrients" here
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