Nutritional Considerations of Pain

Published on
July 23, 2012

Below is a list of various nutrients that affect a person affected with body pain.

  • Cysteine - reduces pain caused by systemic inflammation due to its potent antioxidant properties.
  • Inositol - in animal studies, treatment with inositol induces antinociception (pain reduction).
  • Oleic Acid - this fatty acid is a precursor of oleamide, an analgesic that affects neurotransmitters such as dopamine, serotonin, acetylcholine and GABA (gamma amino butyric acid), all of which play a role in pain signaling.
  • Carnitine - deficiency of this amino acid may manifest as muscle weakness, pain (myalgia) or neuropathy. Supplementation reduces several types of chronic pain.
  • Magnesium - lowers pain by blocking NMDA receptors in spinal cord; effective in reducing post-operative pain.
  • Minerals:some text
    • Manganese - a cofactor for the potent antioxidant superoxide dismutase, which fights free radicals, a known source of pain.
    • Copper - supplementation can relieve arthritic pain.
    • Selenium - treatment with this mineral improves muscle pain in deficient patients.
    • Zinc & Calcium - research suggests both play a role in the transmission of pain signals through nerves.
  • Choline - activates specific receptors in brain and spine that lower acute pain.
  • Vitamin B1, B2, B6, B12 - these produce a dose dependent decrease in various kinds of pain (heat, pressure, chemical); increases sensitivity to pain meds; their effect is likely mediated through serotonergic neurotransmitters.
  • Vitamin D - deficiency often presents clinically as muscle or bone pain.
  • Lipoic Acid - very effective treatment for neuropathic pain.
  • Antioxidants - clinical trials show antioxidant therapy is an effective treatment for chronic painsome text
    • Vitamin E - reduces neuropathic pain
    • Vitamin C - can lower morphine consumption after surgery
    • Coenzyme Q10 - relieves statin-induced myopathy.